Poly(glycidyl nitrate)
PGN
CAS: 27814-48-8
Molecular Formula: C3H5NO4
Poly(glycidyl nitrate) - Names and Identifiers
| Name | PGN |
| Synonyms | PGN Peptidoglycan Poly(glycidyl nitrate) Glycidyl nitrate homopolymer Oxiranemethanol nitrate, homopolymer Peptidoglycan from Saccharomyces cerevisiae |
| CAS | 27814-48-8 |
Poly(glycidyl nitrate) - Physico-chemical Properties
| Molecular Formula | C3H5NO4 |
| Molar Mass | 119.08 |
| Storage Condition | -20°C |
Poly(glycidyl nitrate) - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-21 |
Poly(glycidyl nitrate) - Reference
| Reference Show more | 1. Zhang, Haiyan, et al. "Cloning and expression study of a Toll-like receptor 2 (tlr2) gene from turbot, Scophthalmus maximus." Fish & shellfish immunology 59 (2016): 137-148.https://doi.org/10.1016/j.fsi.2016.10.001 2. [IF=4.581] Haiyan Zhang et al."Cloning and expression study of a Toll-like receptor 2 (tlr2) gene from turbot, Scophthalmus maximus."Fish Shellfish Immun. 2016 Dec;59:137 3. [IF=10.588] Meizhen Wang et al."Interaction with teichoic acids contributes to highly effective antibacterial activity of graphene oxide on Gram-positive bacteria."J Hazard Mater. 2021 Jun;412:125333 4. [IF=4.581] Xin-Yan Shang-Guan et al."A C-type lectin with a single CRD from Onychostoma macrolepis mediates immune recognition against bacterial challenge."Fish Shellfish Immun. 2021 Aug;115:160 5. [IF=4.407] Xin-Yan Shang-Guan et al."A C-type lectin (OmCTL) in Onychostoma macrolepis: Binding ability to LPS, PGN and agglutinating activity against bacteria."Mol Immunol. 2021 Apr;132:21 6. [IF=3.636] Hongzhou Xu et al."Molecular characterization and antibacterial ability of galectin-3 and galectin-9 in Onychostoma macrolepis."Dev Comp Immunol. 2022 Mar;128:104333 |
Poly(glycidyl nitrate) - Introduction
PGN(PGN) is a mixture of polypeptides and polysaccharides, which has a variety of biological activities and pharmacological effects. The following is a description of the nature, use, preparation and safety information of PGN:
Nature:
1. PGN is a positively charged aggregate composed of polypeptide and polysaccharide molecules.
2. it usually presents a gelatinous or powdery form.
3. PGN has good solubility in water, but low solubility in organic solvents.
4. It has strong antibacterial, antiviral and immunomodulatory activities, and has the effect of promoting wound healing.
Use:
1. PGN is widely used in the pharmaceutical field as a drug adjuvant to improve the bioavailability and stability of drugs.
2. It can be used to prepare drug delivery systems, such as nanoparticles and colloidal carriers, for targeted drug delivery and controlled drug release.
3. PGN can also be used as an additive in cell culture to promote cell growth and increase cell adhesion.
4. Other applications include the food industry and cosmetics.
Preparation Method:
There are many methods for preparing PGN. Common methods include acid hydrolysis, enzymatic hydrolysis, and chemical synthesis. Among them, acid hydrolysis is the most commonly used preparation method, and natural polypeptides and polysaccharides are hydrolyzed by adding an appropriate amount of acidic solution to obtain PGN.
Safety Information:
1. PGN is considered to be relatively safe within a certain range and can be used as a pharmaceutical and food additive.
2. but for certain groups of people, such as pregnant women, children and people allergic to PGN, should be used with caution.
3. When using PGN, you need to pay attention to avoid high temperature and long-term exposure to prevent its degradation.
4. Although PGN is widely accepted as a biocompatible and low-toxicity substance, it is still necessary to follow the corresponding safe operation regulations during use.
Nature:
1. PGN is a positively charged aggregate composed of polypeptide and polysaccharide molecules.
2. it usually presents a gelatinous or powdery form.
3. PGN has good solubility in water, but low solubility in organic solvents.
4. It has strong antibacterial, antiviral and immunomodulatory activities, and has the effect of promoting wound healing.
Use:
1. PGN is widely used in the pharmaceutical field as a drug adjuvant to improve the bioavailability and stability of drugs.
2. It can be used to prepare drug delivery systems, such as nanoparticles and colloidal carriers, for targeted drug delivery and controlled drug release.
3. PGN can also be used as an additive in cell culture to promote cell growth and increase cell adhesion.
4. Other applications include the food industry and cosmetics.
Preparation Method:
There are many methods for preparing PGN. Common methods include acid hydrolysis, enzymatic hydrolysis, and chemical synthesis. Among them, acid hydrolysis is the most commonly used preparation method, and natural polypeptides and polysaccharides are hydrolyzed by adding an appropriate amount of acidic solution to obtain PGN.
Safety Information:
1. PGN is considered to be relatively safe within a certain range and can be used as a pharmaceutical and food additive.
2. but for certain groups of people, such as pregnant women, children and people allergic to PGN, should be used with caution.
3. When using PGN, you need to pay attention to avoid high temperature and long-term exposure to prevent its degradation.
4. Although PGN is widely accepted as a biocompatible and low-toxicity substance, it is still necessary to follow the corresponding safe operation regulations during use.
Last Update：2024-04-09 19:04:54
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Product Name: PGN Visit Supplier Webpage Request for quotation
CAS: 27814-48-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 27814-48-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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